Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 214
interventional 169
Observational 43
Registry 2

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Behavioral 52
Device 23
Drug 23
Drug|placebo 23
Other 20
Procedure 7
Behavioral|Drug|placebo 5
Behavioral|Other 4
Behavioral|placebo 2
Drug|Other 2
Behavioral|Biological|Device 1
Behavioral|Drug 1
Behavioral|Drug|Other|Radiation 1
Device|Other 1
Device|placebo 1
Drug|Other|placebo 1
placebo 1
Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 96
France 13
NA 8
Canada 7
China 7
Brazil 5
Netherlands 4
Germany 3
Italy 3
Australia 2
Sweden 2
Taiwan 2
Austria|Germany 1
Belgium 1
Denmark 1
Hong Kong 1
India 1
Korea, Republic of 1
Malaysia 1
Norway 1
Pakistan 1
Spain 1
Switzerland 1
Thailand 1
Turkey 1
United Kingdom 1
United States|Canada 1
United States|Spain 1
Vietnam 1

Sites per Study

Site_count Study_Count
1 142
2 11
3 4
4 4
5 2
6 1
13 1
16 1
18 1
19 1
24 1

Phase

Phase Study_Count
N/A 94
Phase 2 26
Phase 4 13
Phase 1 10
Phase 1/Phase 2 10
Phase 3 9
Phase 2/Phase 3 5
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 22
2 105
3 22
4 8
5 2
6 1
7 1
8 1
NA 7

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 15.0 2.0000 8.00 8.0 0.0000 30 29.0000 8
1st Qu. 23.5 40.0000 18.75 20.0 31.5000 30 89.0000 38
Median 32.0 79.5000 32.00 47.0 79.0000 40 201.0000 54
Mean 32.0 134.8404 42.10 59.9 111.3462 123 313.2222 137
3rd Qu. 40.5 178.0000 49.00 107.0 184.0000 207 270.0000 218
Max. 49.0 961.0000 147.00 126.0 320.0000 308 1246.0000 500

Trial Group Type

group_type Group_Count
Experimental 173
Active Comparator 87
Placebo Comparator 44
No Intervention 22
Other 19
Sham Comparator 16
NA 7

Intervention Model

intervention_model Study_Count
Parallel Assignment 124
Single Group Assignment 28
Crossover Assignment 13
Factorial Assignment 3
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 119
Health Services Research 12
Basic Science 11
Other 9
Supportive Care 6
Diagnostic 4
Prevention 3
Screening 2
NA 2
Device Feasibility 1

Observational Studies

Studies by Country

Country Study_Count
United States 15
France 11
NA 5
Australia 2
Germany 2
Italy 2
Turkey 2
Canada 1
China 1
Egypt 1
Korea, Republic of 1

Sites per Study

Site_count Study_Count
1 37
2 2
5 1
6 1
8 1
22 1

Enrollment Metrics

Measure Observational
Min 12.00
1st Qu 74.25
Median 215.00
Mean 4881.31
3rd Qu 917.00
Max 164923.00

Observation Model

observational_model Study_Count
Cohort 18
Other 8
NA 7
Case-Control 5
Case-Only 4
Case Control 1

Time Perspective

time_perspective Study_Count
Prospective 22
Cross-Sectional 9
Retrospective 7
NA 3
Other 2

Registries

Studies by Country

Country Study_Count
Norway 1
United States 1

Sites per Study

Site_count Study_Count
1 1
3 1

Enrollment Metrics

Measure Registries
Min 104
1st Qu 6328
Median 12552
Mean 12552
3rd Qu 18776
Max 25000

Registry Model

observational_model Study_Count
Cohort 1
Other 1

Time Perspective

time_perspective Study_Count
Other 1
Prospective 1

Follow-up

target_duration Study_Count
1 Day 1
25 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT02153749 Effects of Brief Training on Craving Regulation https://ClinicalTrials.gov/show/NCT02153749 Completed Yale University 2019-07-31
NCT03826966 Comprehensive CBT (Cognitive Behavioral Therapy) Via reSET App https://ClinicalTrials.gov/show/NCT03826966 Completed Milton S. Hershey Medical Center 2020-01-31
NCT03471182 Investigation of Cocaine Addiction Using mGluR5 PET and fMRI https://ClinicalTrials.gov/show/NCT03471182 Recruiting Yale University 2022-06-30
NCT03347474 Deep Brain Stimulation of Nucleus Accumbens for Methamphetamine Addiction https://ClinicalTrials.gov/show/NCT03347474 Recruiting Ruijin Hospital 2020-09-20
NCT03328637 Smartphone Addiction and Its Effect on Mental Health: An Evidence Based Intervention for Amelioration https://ClinicalTrials.gov/show/NCT03328637 Completed International Islamic University, Islamabad 2018-07-30
NCT03318081 The Application of Cognitive Rehabilitation Therapy for Amphetamine-type Stimulants Addiction https://ClinicalTrials.gov/show/NCT03318081 Completed Shanghai Mental Health Center 2017-12-31
NCT03287180 Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use https://ClinicalTrials.gov/show/NCT03287180 Recruiting Emory University 2020-08-30
NCT03278496 Recovery Housing and Drug Abuse Treatment Outcome https://ClinicalTrials.gov/show/NCT03278496 Completed Johns Hopkins University 2008-06-30
NCT03232112 Does Treatment With GLP-1 Reduce Alcohol Intake in Patients With Alcohol Dependence? https://ClinicalTrials.gov/show/NCT03232112 Active, not recruiting Psychiatric Centre Rigshospitalet 2020-03-15
NCT03230669 Computer-assisted Delivery of Cognitive Behavioral Therapy for Mental Health and Addictions in Canada https://ClinicalTrials.gov/show/NCT03230669 Active, not recruiting University of Prince Edward Island 2018-03-31
NCT03221985 ESM Pilot: Mobile Phones and Psychology https://ClinicalTrials.gov/show/NCT03221985 Completed Maastricht University Medical Center 2017-05-31
NCT03174730 Mindset Intervention for Nicotine Dependence https://ClinicalTrials.gov/show/NCT03174730 Completed Fred Hutchinson Cancer Research Center 2018-01-17
NCT03089983 Addiction, HIV and Tuberculosis in Malaysian Criminal Justice Settings https://ClinicalTrials.gov/show/NCT03089983 Recruiting Yale University 2022-04-30
NCT03027687 Effects of Repetitive tDCS on ad Libitum Smoking Behavior: EMA and EEG Study https://ClinicalTrials.gov/show/NCT03027687 Completed Erasmus Medical Center 2018-03-31
NCT03025321 Effects of tDCS on Craving, Relapse and Cognitive Functions Among Patients With Cocaine Use Disorder https://ClinicalTrials.gov/show/NCT03025321 Completed Erasmus Medical Center 2018-11-26
NCT03015597 Pilot Study of Contingency Management for Smoking Cessation https://ClinicalTrials.gov/show/NCT03015597 Completed King’s College London 2017-09-30
NCT02966873 Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD) https://ClinicalTrials.gov/show/NCT02966873 Recruiting Medical University of South Carolina 2021-08-01
NCT02939352 The Effects of Theta Burst Stimulation on the Brain Response to Drug and Alcohol Cues https://ClinicalTrials.gov/show/NCT02939352 Completed Medical University of South Carolina 2015-12-31
NCT02939339 Theta Burst TMS as a Tool to Change Smoking Behavior https://ClinicalTrials.gov/show/NCT02939339 Completed Medical University of South Carolina 2017-08-01
NCT02929485 Dopaminergic Modulation of Frontostriatal Function With a Dopamine Agonist and COMT Inhibitor https://ClinicalTrials.gov/show/NCT02929485 Completed University of California, Berkeley 2018-01-31
NCT02893514 Leveraging Technology to Address Unhealthy Drug Use in Primary Care Settings https://ClinicalTrials.gov/show/NCT02893514 Completed NYU Langone Health 2019-03-30
NCT02870218 Abuse Liability of Reduced Nicotine Content Cigarettes in the Context of Concurrent E-Cigarette Use https://ClinicalTrials.gov/show/NCT02870218 Recruiting Rose Research Center, LLC 2020-06-30
NCT02837510 Neural Mechanisms Associated With Risk of Smoking Relapse https://ClinicalTrials.gov/show/NCT02837510 Recruiting University of Pennsylvania 2020-12-31
NCT02836080 Integrated Collaborative Care Teams for Youth With Mental Health and/or Addiction Challenges (YouthCan IMPACT) https://ClinicalTrials.gov/show/NCT02836080 Recruiting Centre for Addiction and Mental Health 2022-12-31
NCT02812810 Evaluation of the Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) Low-frequency on Craving in Smoking Dependence https://ClinicalTrials.gov/show/NCT02812810 Completed Centre Hospitalier Universitaire Dijon 2015-02-28
NCT02801357 Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose Reduction https://ClinicalTrials.gov/show/NCT02801357 Completed US WorldMeds LLC 2016-08-31
NCT02757716 Addiction Remission and Addiction Transfer After Bariatric Surgery https://ClinicalTrials.gov/show/NCT02757716 Completed Sana Klinikum Offenbach 2019-01-31
NCT02739490 Effect of the Pelvic Loin Musculature Training on the Dynamic Hip Stabilization https://ClinicalTrials.gov/show/NCT02739490 Completed Universidade Estadual do Centro-Oeste 2014-10-31
NCT02713815 Novel Intervention for Amphetamine-type Stimulants Addiction https://ClinicalTrials.gov/show/NCT02713815 Completed Shanghai Mental Health Center 2019-07-31
NCT02656745 Clinical Trial of Smoking Cessation Mobile Phone Program https://ClinicalTrials.gov/show/NCT02656745 Completed Click Therapeutics, Inc. 2016-09-30
NCT02626494 Neurobiological Adaptations and Pharmacological Interventions in Cocaine Addiction https://ClinicalTrials.gov/show/NCT02626494 Completed Psychiatric University Hospital, Zurich 2017-03-31
NCT02624284 tDCS Effects on Resisting Smoking: Dose Ranging Study https://ClinicalTrials.gov/show/NCT02624284 Completed University of Pennsylvania 2018-03-31
NCT02556060 Lamotrigine for Ketamine Dependence Trial https://ClinicalTrials.gov/show/NCT02556060 Completed Taipei City Hospital 2017-05-01
NCT02540174 Alcohol and Tobacco Consumption in Patients With Head and Neck or Lung Cancer : Interest of an Addiction Treatment https://ClinicalTrials.gov/show/NCT02540174 Completed Centre Oscar Lambret 2016-11-09
NCT02499029 N-acetylcysteine in the Treatment of PTSD and Addiction https://ClinicalTrials.gov/show/NCT02499029 Completed Medical University of South Carolina 2014-09-30
NCT02482233 The END Perioperative Smoking Pilot Study https://ClinicalTrials.gov/show/NCT02482233 Completed University of California, San Francisco 2016-05-31
NCT02481362 Food Choices in Healthy Weight Women https://ClinicalTrials.gov/show/NCT02481362 Completed The University of Tennessee, Knoxville 2016-05-31
NCT02398487 Personal Vaporizer vs Cigalike https://ClinicalTrials.gov/show/NCT02398487 Completed Universita degli Studi di Catania 2015-12-31
NCT02378181 Testing the Effectiveness of a Graphic Novel Health Education Curriculum for Patients With Addiction https://ClinicalTrials.gov/show/NCT02378181 Completed Treatment Research Institute 2017-04-15
NCT02362698 Clinical Research of Electro-acupuncture Combined Psychological Intervention on Internet Addiction Disorder https://ClinicalTrials.gov/show/NCT02362698 Completed Chengdu University of Traditional Chinese Medicine 2011-10-31
NCT02334956 Linking fMRI to Mobile Technologies in Addiction Research: Pathophysiology of Executive Deficits, Craving and Substance Use https://ClinicalTrials.gov/show/NCT02334956 Completed University Hospital, Bordeaux 2018-01-10
NCT02243670 Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy https://ClinicalTrials.gov/show/NCT02243670 Completed AiCure 2017-03-31
NCT02154685 Extinction Updating in Reconsolidation https://ClinicalTrials.gov/show/NCT02154685 Completed Medical University of South Carolina 2015-09-30
NCT02153775 Progressive Muscle Relaxation and Cigarette Craving https://ClinicalTrials.gov/show/NCT02153775 Completed Chulalongkorn University 2012-11-30
NCT02146014 Effects of Transcranial Direct Current Stimulation on Cigarette Addiction https://ClinicalTrials.gov/show/NCT02146014 Completed University of Brasilia 2015-12-31
NCT02124200 High Cessation Rates in Smokers Using Personal Vaporizers https://ClinicalTrials.gov/show/NCT02124200 Completed Universita degli Studi di Catania 2013-11-30
NCT02119949 Working Memory Training for Substance Dependent Individuals https://ClinicalTrials.gov/show/NCT02119949 Completed Erasmus Medical Center 2014-06-30
NCT02112695 Opioid System Cerebral Activity in Endurance Sportswomen - Addiction or Denutrition ? [11C]Diprenorphine PET Study https://ClinicalTrials.gov/show/NCT02112695 Completed Centre Hospitalier Universitaire de Saint Etienne 2017-07-06
NCT02091167 Bilateral Prefrontal Modulation in Crack-cocaine Addiction https://ClinicalTrials.gov/show/NCT02091167 Completed Federal University of Espirito Santo 2018-07-31
NCT01314001 Pharmacogenetics of Nicotine Addiction Treatment https://ClinicalTrials.gov/show/NCT01314001 Completed University of Pennsylvania 2013-12-31
NCT01288183 Anodal Transcranial Direct Current Stimulation (tDCS) in the Treatment of Tobacco Addiction https://ClinicalTrials.gov/show/NCT01288183 Completed Hôpital le Vinatier 2014-12-31
NCT01281202 Vigabatrin for the Treatment of Cocaine Dependency https://ClinicalTrials.gov/show/NCT01281202 Completed National Institute on Drug Abuse (NIDA) 2012-10-31
NCT02046408 Computer-Facilitated 5A’s for Smoking Cessation in Primary Care https://ClinicalTrials.gov/show/NCT02046408 Completed University of California, San Francisco 2015-09-30
NCT03538652 Just-In-Time Adaptive Interventions for Addictive Behaviors https://ClinicalTrials.gov/show/NCT03538652 Recruiting National Institutes of Health Clinical Center (CC) 2023-05-01
NCT03356509 Effect of Exercise on Chocolate Addiction https://ClinicalTrials.gov/show/NCT03356509 Completed University of Miami 2018-09-15
NCT02000921 Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors https://ClinicalTrials.gov/show/NCT02000921 Completed University of Minnesota 2015-09-30
NCT01965704 Can Ondansetron Prevent Neonatal Abstinence Syndrome (NAS) in Babies Born to Narcotic-dependent Women https://ClinicalTrials.gov/show/NCT01965704 Recruiting Stanford University 2021-03-30
NCT01929343 Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving https://ClinicalTrials.gov/show/NCT01929343 Completed University of Texas Southwestern Medical Center 2016-03-31
NCT01887366 Efficacy and Safety of TV-1380 as Treatment for Facilitation of Abstinence in Cocaine-Dependent Subjects https://ClinicalTrials.gov/show/NCT01887366 Completed Teva Pharmaceutical Industries 2014-09-30
NCT01878006 Genetic Effects on Dopamine Response to an Opiate https://ClinicalTrials.gov/show/NCT01878006 Completed National Institutes of Health Clinical Center (CC) 2017-04-27
NCT01873989 Testosterone Replacement for Male Opioid Agonist Maintained Patients https://ClinicalTrials.gov/show/NCT01873989 Completed Yale University 2015-01-31
NCT01870882 Attention Training for Opioid-maintained Cocaine Users https://ClinicalTrials.gov/show/NCT01870882 Completed Yale University 2014-12-31
NCT01830842 Acute and Chronic Nicotine Modulation of Reinforcement Learning https://ClinicalTrials.gov/show/NCT01830842 Completed Duke University 2016-08-31
NCT01795755 YATEP - The Impact of Horse Assisted Therapy (HAT) on Treatment Outcomes https://ClinicalTrials.gov/show/NCT01795755 Completed Oslo University Hospital 2016-06-30
NCT01785147 Efficacy and Safety of BP1.4979 in Smoking Cessation https://ClinicalTrials.gov/show/NCT01785147 Completed Bioprojet 2014-07-31
NCT01733199 Behavioural Addictions Occurring During a Dopaminergic Treatment Prescribe Under Parkinson’s Disease: Study of the Psychopathological, Neurological, Pharmacokinetic and Genetic Profiles https://ClinicalTrials.gov/show/NCT01733199 Completed Nantes University Hospital 2016-05-31
NCT01656707 Adaptive Treatment for Adolescent Cannabis Use Disorders https://ClinicalTrials.gov/show/NCT01656707 Completed UConn Health 2016-07-31
NCT01632735 Mobile Continuing Care Approach for Youth https://ClinicalTrials.gov/show/NCT01632735 Completed Azusa Pacific University 2014-12-31
NCT01591239 Home-Based Program to Help Parents of Drug Abusing Adolescents https://ClinicalTrials.gov/show/NCT01591239 Completed Treatment Research Institute 2016-04-30
NCT01590251 Yoga for Pain and Opioid Dependence https://ClinicalTrials.gov/show/NCT01590251 Completed Yale University 2014-11-30
NCT01587196 CURE Addiction Center of Excellence: Brain Mechanisms of Relapse and Recovery https://ClinicalTrials.gov/show/NCT01587196 Enrolling by invitation University of Pennsylvania 2021-01-31
NCT01586689 Evaluating Alternative Aftercare Models for Ex-offenders https://ClinicalTrials.gov/show/NCT01586689 Completed National Institute on Drug Abuse (NIDA) 2013-06-30
NCT01548638 Effect of Galantamine on Smoking Abstinence https://ClinicalTrials.gov/show/NCT01548638 Completed University of Pennsylvania 2012-08-31
NCT01531153 Cognitive Enhancement as a Target for Cocaine Pharmacotherapy https://ClinicalTrials.gov/show/NCT01531153 Completed Yale University 2016-06-30
NCT01498549 Cognitive Effects of Atomoxetine in Humans: Genetic Moderators https://ClinicalTrials.gov/show/NCT01498549 Completed Yale University 2013-07-31
NCT01457872 Malmö Treatment Referral and Intervention Study https://ClinicalTrials.gov/show/NCT01457872 Completed Region Skane 2013-04-30
NCT01457391 Cognitive Behavioral Therapy (CBT) for Posttraumatic Stress Disorder (PTSD) in Community Addiction Treatment https://ClinicalTrials.gov/show/NCT01457391 Completed Dartmouth-Hitchcock Medical Center 2014-04-30
NCT01456338 Cognitive Behavioral Therapy for Post Traumatic Stress Disorder in Addiction Treatment https://ClinicalTrials.gov/show/NCT01456338 Completed Dartmouth-Hitchcock Medical Center 2009-04-30
NCT01438944 Evaluation of Transdermal Nicotine Replacement Therapy (NRT) Activity Through Metabolic Induction https://ClinicalTrials.gov/show/NCT01438944 Completed The Queen Elizabeth Hospital 2015-07-31
NCT01434589 Effects of a Manualized Short-term Treatment of Internet and Computer Game Addiction https://ClinicalTrials.gov/show/NCT01434589 Completed Johannes Gutenberg University Mainz 2017-06-30
NCT01391624 Study on the Possible Effects of Diet Supplementation With Essential Fatty Acids in Chocolate Craving Volunteers https://ClinicalTrials.gov/show/NCT01391624 Completed Federal University of São Paulo 2011-01-31
NCT01344382 Family Training Program for Parents of Substance Using Adolescents https://ClinicalTrials.gov/show/NCT01344382 Completed Treatment Research Institute 2016-05-31
NCT01337297 Prefrontal Cortex Stimulation as Treatment for Crack-cocaine Addiction https://ClinicalTrials.gov/show/NCT01337297 Completed Federal University of Espirito Santo 2012-11-30
NCT04432064 Temporal Interference Neurostimulation and Addiction https://ClinicalTrials.gov/show/NCT04432064 Active, not recruiting Indiana University 2021-05-31
NCT04356274 Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care https://ClinicalTrials.gov/show/NCT04356274 Enrolling by invitation Palo Alto Veterans Institute for Research 2024-08-31
NCT04299074 Smartphone Addiction and Physical Activity https://ClinicalTrials.gov/show/NCT04299074 Completed Pamukkale University 2019-03-20
NCT04293978 Virtual Reality Relaxation for Addiction Inpatients https://ClinicalTrials.gov/show/NCT04293978 Recruiting Karolinska Institutet 2020-04-20
NCT03347643 The Effectiveness of tDCS on Internet Game Addiction https://ClinicalTrials.gov/show/NCT03347643 Completed Seoul National University Hospital 2019-09-01
NCT04133688 Mobile App in Addiction https://ClinicalTrials.gov/show/NCT04133688 Recruiting Assistance Publique - Hôpitaux de Paris 2020-04-30
NCT04133597 The Relationship Among Electroencephalography,Skin Conductance Response,Heart Rate Variability and Mental Health Among Smartphone Users After Receiving Texting or Calling https://ClinicalTrials.gov/show/NCT04133597 Completed Kaohsiung Medical University Chung-Ho Memorial Hospital 2019-01-31
NCT03333460 Transcranial Magnetic Stimulation for Cocaine Addiction https://ClinicalTrials.gov/show/NCT03333460 Recruiting ITAB - Institute for Advanced Biomedical Technologies 2020-12-01
NCT04125303 The Effectiveness of a Brief Motivational Nursing Intervention https://ClinicalTrials.gov/show/NCT04125303 Completed Cardenal Herrera University 2016-10-31
NCT04105712 The Biobehavioral Impact of Diet Quality on Affect and Craving https://ClinicalTrials.gov/show/NCT04105712 Recruiting University of Michigan 2021-05-31
NCT04086459 PET/MRI Study on the Neurological Mechanism of rTMS Treatment for Heroin Addiction https://ClinicalTrials.gov/show/NCT04086459 Recruiting Tang-Du Hospital 2021-07-01
NCT04059497 Short-bout Handgrip Exercise Intervention https://ClinicalTrials.gov/show/NCT04059497 Recruiting The University of Hong Kong 2020-01-31
NCT04055272 A Mobile Text Messaging Intervention for Indoor Tanning Addiction https://ClinicalTrials.gov/show/NCT04055272 Recruiting Georgetown University 2021-03-31
NCT03967418 Behavioral Addictions and Related NeuroCOgnitive Aspects https://ClinicalTrials.gov/show/NCT03967418 Recruiting Nantes University Hospital 2022-10-31
NCT03952455 Deep Brain Stimulation of the Bilateral Nucleus Accumbens for Patients With Methadone Maintenance Treatment https://ClinicalTrials.gov/show/NCT03952455 Recruiting Ruijin Hospital 2021-06-01
NCT03910608 Paired Associative Stimulation in Methamphetamine Addiction https://ClinicalTrials.gov/show/NCT03910608 Recruiting Shanghai Mental Health Center 2021-03-31
NCT03922646 Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder https://ClinicalTrials.gov/show/NCT03922646 Recruiting Laureate Institute for Brain Research, Inc. 2022-03-01
NCT03903159 Piloting “Positive Peer Journaling” a Journaling Practice to Support Recovery From Addiction https://ClinicalTrials.gov/show/NCT03903159 Completed University of Minnesota 2019-09-30
NCT03833583 tDCS to Reduce Craving in Cocaine Addiction https://ClinicalTrials.gov/show/NCT03833583 Recruiting Soterix Medical 2019-09-30
NCT03810924 Stress-related Predictor Profiles in Human Addiction https://ClinicalTrials.gov/show/NCT03810924 Recruiting Central Institute of Mental Health, Mannheim 2023-07-31
NCT03765281 Exploring the Outcomes of System Supports for Youth With Mental Illness and/or Addictions and Their Families https://ClinicalTrials.gov/show/NCT03765281 Active, not recruiting Sunnybrook Health Sciences Centre 2019-06-30
NCT03694327 Innovative Digital Therapeutic for Smoking Cessation https://ClinicalTrials.gov/show/NCT03694327 Completed My Digital Study 2019-03-14
NCT03678051 CBT4CBT for Women in Residential Treatment for Substance Use Disorders https://ClinicalTrials.gov/show/NCT03678051 Completed Virginia Commonwealth University 2020-01-18
NCT03674970 Effects of Random Nicotine Delivery on Smoking Cessation https://ClinicalTrials.gov/show/NCT03674970 Completed Milton S. Hershey Medical Center 2019-11-25
NCT03606759 Evaluation of the Efficacy of the Individually Adjusted Therapy Scale (ATI) on the Addiction Severity https://ClinicalTrials.gov/show/NCT03606759 Recruiting University Hospital, Bordeaux 2021-04-30
NCT03589118 Qi Gong as a Method of Craving Reduction in Severe Addict Patients https://ClinicalTrials.gov/show/NCT03589118 Recruiting Assistance Publique - Hôpitaux de Paris 2020-12-31
NCT03576768 QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt https://ClinicalTrials.gov/show/NCT03576768 Completed Medical University of South Carolina 2019-10-25
NCT03500835 An Addiction-Based Mobile Health Weight Loss Intervention With Coaching https://ClinicalTrials.gov/show/NCT03500835 Recruiting Children’s Hospital Los Angeles 2021-01-31
NCT03423667 Efficacy of N-acetylcysteine on the Craving Symptoms of Abstinent Hospitalized Patients With Cocaine Addiction https://ClinicalTrials.gov/show/NCT03423667 Recruiting Brugmann University Hospital 2022-12-31
NCT03412669 The Preliminary Evaluation of Supporting Addiction Affected Families Effectively https://ClinicalTrials.gov/show/NCT03412669 Completed Sangath 2016-11-30
NCT01262261 Re-Treatment Study of Probuphine in Opioid Addiction https://ClinicalTrials.gov/show/NCT01262261 Completed Titan Pharmaceuticals 2011-11-30
NCT01228175 Effectiveness of Varenicline: Testing Individual Differences https://ClinicalTrials.gov/show/NCT01228175 Completed The Mind Research Network 2015-02-28
NCT01211418 Integrative Meditation (IM) for Cocaine Addiction https://ClinicalTrials.gov/show/NCT01211418 Completed University of Maryland, Baltimore 2012-03-31
NCT01211106 Integrated vs Sequential Treatment for PTSD and Addiction https://ClinicalTrials.gov/show/NCT01211106 Completed VA Office of Research and Development 2016-03-31
NCT01186315 Post-traumatic Stress Disorder (PTSD), Addiction, and Virtual Reality https://ClinicalTrials.gov/show/NCT01186315 Completed Duke University 2013-10-31
NCT01184040 Extending Contingency Management’s Benefits With Progressively Increasing Variable Interval Prize Reinforcement https://ClinicalTrials.gov/show/NCT01184040 Completed UConn Health 2012-03-31
NCT01171677 Impact of Exercise and Affirmations (IntenSati) on Addiction-related Cognitive and Psychosocial Deficits https://ClinicalTrials.gov/show/NCT01171677 Completed NYU Langone Health 2010-11-30
NCT01103531 Exercise to Improve Outcomes of Treatment for Methamphetamine Users https://ClinicalTrials.gov/show/NCT01103531 Completed University of California, Los Angeles 2015-07-31
NCT01067846 Cognitive Enhancement and Relapse Prevention in Cocaine Addiction https://ClinicalTrials.gov/show/NCT01067846 Completed University of Arkansas 2012-01-31
NCT01062932 Investigation of Cycloserine as a Smoking Cessation Treatment https://ClinicalTrials.gov/show/NCT01062932 Completed Baylor College of Medicine 2010-05-31
NCT01056926 Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction https://ClinicalTrials.gov/show/NCT01056926 Completed Duke University 2011-11-30
NCT01015170 STOP Study: Effectiveness of Zyban in a Clinical Population https://ClinicalTrials.gov/show/NCT01015170 Completed Centre for Addiction and Mental Health 2015-10-31
NCT00984360 Study of Naltrexone for Methamphetamine Addiction https://ClinicalTrials.gov/show/NCT00984360 Completed California Pacific Medical Center Research Institute 2011-07-31
NCT00935103 The Effectiveness of Skill-Based HIV Psychoeducation in IV-Drug Abuser for Reducing High-risk Behavior https://ClinicalTrials.gov/show/NCT00935103 Completed Iran University of Medical Sciences 2011-03-31
NCT00934141 Evaluating Improvement Strategies in Addiction Treatment https://ClinicalTrials.gov/show/NCT00934141 Completed University of Wisconsin, Madison 2009-07-31
NCT00879996 Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients https://ClinicalTrials.gov/show/NCT00879996 Completed State University of New York at Buffalo 2011-10-31
NCT00842036 CRAFT Behavior Therapy: Treatment Entry Component https://ClinicalTrials.gov/show/NCT00842036 Completed Treatment Research Institute 2009-12-31
NCT03764969 Modification of Goal-directed and Habitual Behavior in Addiction https://ClinicalTrials.gov/show/NCT03764969 Recruiting Central Institute of Mental Health, Mannheim 2023-07-31
NCT04202926 Repetitive dTMS Intervention for Methamphetamine Addiction https://ClinicalTrials.gov/show/NCT04202926 Recruiting Shanghai Mental Health Center 2020-12-30
NCT01822587 Enhancing Disrupted Reconsolidation: Impact on Cocaine Craving https://ClinicalTrials.gov/show/NCT01822587 Completed Medical University of South Carolina 2018-11-05
NCT01550341 HIV, Buprenorphine, and the Criminal Justice System https://ClinicalTrials.gov/show/NCT01550341 Completed Yale University 2015-11-30
NCT03345394 Effectiveness of Contingency Management in the Treatment of Crack Addiction in Brazil https://ClinicalTrials.gov/show/NCT03345394 Recruiting Federal University of São Paulo 2019-09-01
NCT03442413 Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction https://ClinicalTrials.gov/show/NCT03442413 Active, not recruiting University of Pennsylvania 2022-09-01
NCT02535702 Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction https://ClinicalTrials.gov/show/NCT02535702 Recruiting National Institutes of Health Clinical Center (CC) 2025-12-31
NCT03454711 Functional Magnetic Resonance Imaging (fMRI) Exploration of Neurocognitive Processes Involved in Food Addiction (FA) in Obese Patients: Towards New Phenotypic Markers for an Optimized Care Pathway https://ClinicalTrials.gov/show/NCT03454711 Recruiting Rennes University Hospital 2022-04-26
NCT01841320 Seek, Test, Treat Strategies for Vietnamese Drug Users: A Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT01841320 Completed Johns Hopkins University 2016-08-31
NCT01621711 Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care https://ClinicalTrials.gov/show/NCT01621711 Active, not recruiting Kaiser Permanente 2020-12-31
NCT00781898 Treatment Study Using Depot Naltrexone (1/6) Philadelphia Coord/Data Mgmt Site https://ClinicalTrials.gov/show/NCT00781898 Completed University of Pennsylvania 2015-08-31
NCT00713479 An Assessment of the Safety of Varenicline in Methamphetamine-dependent Volunteers https://ClinicalTrials.gov/show/NCT00713479 Completed University of California, Los Angeles 2009-08-31
NCT00701532 Brain Imaging Study of the Effects of Modafinil in Cocaine Addiction https://ClinicalTrials.gov/show/NCT00701532 Completed Assistance Publique - Hôpitaux de Paris 2012-10-31
NCT00685178 Clinical Trial of Topiramate for Cocaine Addiction https://ClinicalTrials.gov/show/NCT00685178 Completed Johns Hopkins University 2011-06-30
NCT00631748 Quetiapine for the Reduction of Cocaine Use https://ClinicalTrials.gov/show/NCT00631748 Completed Seattle Institute for Biomedical and Clinical Research 2010-07-31
NCT00630682 A Pilot Trial of Dextroamphetamine for Methamphetamine Dependence https://ClinicalTrials.gov/show/NCT00630682 Completed California Pacific Medical Center Research Institute 2009-03-31
NCT00626834 Vigabatrin Ph 1 Cocaine Interaction Study https://ClinicalTrials.gov/show/NCT00626834 Completed National Institute on Drug Abuse (NIDA) 2010-10-31
NCT00607360 Integration of the Therapeutic Workplace in Drug Court https://ClinicalTrials.gov/show/NCT00607360 Completed National Institute on Drug Abuse (NIDA) NA
NCT00586534 Developing Computer Based Treatments for Addiction https://ClinicalTrials.gov/show/NCT00586534 Completed Duke University 2014-10-31
NCT00567814 A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine Addiction https://ClinicalTrials.gov/show/NCT00567814 Completed Embera NeuroTherapeutics, Inc. 2008-11-30
NCT00565422 Efficacy of Escitalopram in the Treatment of Internet Addiction https://ClinicalTrials.gov/show/NCT00565422 Completed Icahn School of Medicine at Mount Sinai NA
NCT00538655 A Pilot Trial of Modafinil for Treatment of Methamphetamine Dependence https://ClinicalTrials.gov/show/NCT00538655 Completed California Pacific Medical Center Research Institute 2009-01-31
NCT00506935 Assessment of GVG for the Treatment of Methamphetamine Dependence https://ClinicalTrials.gov/show/NCT00506935 Completed Baylor College of Medicine 2008-04-30
NCT00499746 The Discriminative Effects of Tramadol in Humans https://ClinicalTrials.gov/show/NCT00499746 Completed National Institute on Drug Abuse (NIDA) 2010-04-30
NCT00495404 Health Outcomes From Opioid Therapy for Chronic Pain https://ClinicalTrials.gov/show/NCT00495404 Completed VA Office of Research and Development NA
NCT00392379 Nicotine Lozenges for Treatment of Smokeless Tobacco Addiction https://ClinicalTrials.gov/show/NCT00392379 Completed Mayo Clinic 2009-03-31
NCT00367302 Buprenorphine Maintenance for Opioid-Addicted Persons in Jail and Post-Release https://ClinicalTrials.gov/show/NCT00367302 Completed National Development and Research Institutes, Inc. 2008-01-31
NCT00350311 Multicomponent Risk Factor Intervention for People With a Severe Mental Illness: a Feasibility Study https://ClinicalTrials.gov/show/NCT00350311 Completed The University of New South Wales 2008-04-30
NCT00349687 Practicing Self-Control Lowers the Risk of Smoking Lapse https://ClinicalTrials.gov/show/NCT00349687 Completed University at Albany 2009-03-31
NCT00317460 Buprenorphine and Integrated HIV Care https://ClinicalTrials.gov/show/NCT00317460 Completed Yale University 2009-10-31
NCT00249457 Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2 https://ClinicalTrials.gov/show/NCT00249457 Completed Johns Hopkins University 2006-01-31
NCT00244699 Integrating Mindfulness-Based Skills Training Into Brief Outpatient Treatment for Substance Abusing Youth https://ClinicalTrials.gov/show/NCT00244699 Completed Centre for Addiction and Mental Health NA
NCT00235729 Lofexidine for Inpatient Opiate Detox https://ClinicalTrials.gov/show/NCT00235729 Completed VA Office of Research and Development 2007-10-31
NCT00225316 Maternal Acupuncture for Substance Abuse https://ClinicalTrials.gov/show/NCT00225316 Completed University of British Columbia 2008-08-31
NCT00218595 DBT Compared to I/GDC for the Treatment of Opiate Addiction in Emotionally Dysregulated Patients. - 1 https://ClinicalTrials.gov/show/NCT00218595 Completed Duke University 2009-06-30
NCT00175357 NAOMI: A Study to Compare Medically-prescribed Heroin With Oral Methadone in Chronic Opiate Addiction https://ClinicalTrials.gov/show/NCT00175357 Completed University of British Columbia 2007-04-30
NCT00798538 Integration of Buprenorphine Into HIV Clinical Settings - Primary Care Model (PCM) https://ClinicalTrials.gov/show/NCT00798538 Completed Yale University 2010-08-31
NCT00685451 Cognitive Therapy for PTSD in Addiction Treatment https://ClinicalTrials.gov/show/NCT00685451 Completed Dartmouth-Hitchcock Medical Center 2006-08-31
NCT00000244 Effects of Dynorphin 1-13 on Heroin Addiction - 1 https://ClinicalTrials.gov/show/NCT00000244 Completed University of Minnesota 1997-03-31

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT02950376 The Novel Addiction Assessment Study in Synthetic Drugs Addiction https://ClinicalTrials.gov/show/NCT02950376 Completed Shanghai Mental Health Center 2018-12-31
NCT02844985 A Study of Gene Polymorphisms Associated With Specific Presentations of Sexual Addiction https://ClinicalTrials.gov/show/NCT02844985 Enrolling by invitation American Foundation for Addiction Research 2020-06-30
NCT02751762 A Prospective Investigation of the Risks of Opioid Misuse, Abuse, and Addiction Among Patients Treated With Opioids for the Treatment of Chronic Pain https://ClinicalTrials.gov/show/NCT02751762 Recruiting Member Companies of the Opioid PMR Consortium 2020-10-31
NCT02671240 Prognosis of Behavioral Addiction in Parkinson’s Disease https://ClinicalTrials.gov/show/NCT02671240 Recruiting University Hospital, Strasbourg, France 2021-10-24
NCT02668549 Cross-Sectional Study to Define and Validate “Doctor/Pharmacy Shopping” as Outcomes Suggestive of Abuse and/or Addiction https://ClinicalTrials.gov/show/NCT02668549 Completed Member Companies of the Opioid PMR Consortium 2017-08-09
NCT02667262 An Observational Study to Develop Algorithms for Identifying Opioid Abuse and Addiction Based on Admin Claims Data https://ClinicalTrials.gov/show/NCT02667262 Completed Member Companies of the Opioid PMR Consortium 2017-05-17
NCT02667210 Study to Eval Relation Btw Doctor/Pharmacy Shopping & Outcomes of Misuse, Diversion, Abuse, Addiction by Med Rec Review https://ClinicalTrials.gov/show/NCT02667210 Completed Member Companies of the Opioid PMR Consortium 2017-06-21
NCT02660619 Validation of PRISM-5-Op, Measure Of Addiction To Prescription Opioid Medication https://ClinicalTrials.gov/show/NCT02660619 Completed Member Companies of the Opioid PMR Consortium 2017-11-28
NCT01036971 Screening Protocol for the Evaluation of Potential Research Subjects https://ClinicalTrials.gov/show/NCT01036971 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT02571400 Prevalence and Predictors of Prolonged Post-surgical Opioid Use: a Prospective Observational Cohort Study https://ClinicalTrials.gov/show/NCT02571400 Completed University of Notre Dame Australia 2016-10-31
NCT02028273 Hippocampal Neurogenesis in Human Subjects https://ClinicalTrials.gov/show/NCT02028273 Completed University of Texas Southwestern Medical Center 2018-01-31
NCT02415322 Cohort Study on Internet Game and Smart Phone Addiction https://ClinicalTrials.gov/show/NCT02415322 Completed National Clinical Research Coordination Center, Seoul, Korea 2018-12-31
NCT02319395 Behavioural Addiction and Genetics in Parkinson’s Disease https://ClinicalTrials.gov/show/NCT02319395 Completed Assistance Publique - Hôpitaux de Paris 2015-11-30
NCT02062736 Observational Study to Assess the Adequacy of Methadone Dosage, in Heroin Addicted Patients in a MMT. https://ClinicalTrials.gov/show/NCT02062736 Completed L.Molteni & C. dei F.lli Alitti-Soc. di Esercizio S.p.A. 2014-02-28
NCT02062723 Observational Study to Assess the Efficacy and Tolerability of Eptadone®, in Heroin Addicted Patients in a MMT https://ClinicalTrials.gov/show/NCT02062723 Completed L.Molteni & C. dei F.lli Alitti-Soc. di Esercizio S.p.A. 2013-02-28
NCT01984177 Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence https://ClinicalTrials.gov/show/NCT01984177 Completed Centre for Addiction and Mental Health 2016-06-30
NCT01788943 Nicotine Receptor Levels and Smoking Cessation https://ClinicalTrials.gov/show/NCT01788943 Completed University of Pennsylvania 2015-07-31
NCT01704573 Nicotinic Receptor Levels After Stopping Smoking https://ClinicalTrials.gov/show/NCT01704573 Completed University of Pennsylvania 2012-03-31
NCT01702142 To Test a Payer/Treatment Agency Intervention to Increase Use of Buprenorphine https://ClinicalTrials.gov/show/NCT01702142 Completed University of Wisconsin, Madison 2016-12-31
NCT01652378 Pharmacologic MRI in Cocaine Addiction https://ClinicalTrials.gov/show/NCT01652378 Completed University of Texas Southwestern Medical Center 2016-08-31
NCT01621607 Individual Differences in Reward and Impulse Control https://ClinicalTrials.gov/show/NCT01621607 Completed National Institutes of Health Clinical Center (CC) NA
NCT01412268 Does Bariatric Surgery Changes Eating Habits and Addiction in Morbid Obesity? https://ClinicalTrials.gov/show/NCT01412268 Completed Bezmialem Vakif University 2012-02-29
NCT04343339 Evolution of Psychoactive Substances Consumption in Connection With COVID-19 Containment https://ClinicalTrials.gov/show/NCT04343339 Recruiting University Hospital, Montpellier 2020-07-30
NCT04337775 The Turkish Version of the Smartphone Impact Scale https://ClinicalTrials.gov/show/NCT04337775 Enrolling by invitation Istanbul University-Cerrahpasa 2020-06-08
NCT04126239 Validation of a Food Addiction Screening Test https://ClinicalTrials.gov/show/NCT04126239 Recruiting Hospices Civils de Lyon 2020-10-31
NCT03772782 Relationship of SmartPhone Use Addiction With Musculoskeletal System and Cognitive Flexibility https://ClinicalTrials.gov/show/NCT03772782 Completed Hacettepe University 2019-06-12
NCT03745339 Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder https://ClinicalTrials.gov/show/NCT03745339 Recruiting National Institutes of Health Clinical Center (CC) 2021-10-01
NCT03706937 The Treatment of Addictions in the Course of Care in Oncology: an Inventory of Fixtures Among Paramedical Professionals https://ClinicalTrials.gov/show/NCT03706937 Completed Institut de Cancérologie de la Loire 2018-12-20
NCT03685162 Observational Study to Evaluate Levomethadone Safety and Effectiveness in Subjects Under Opioid Maintenance Treatment https://ClinicalTrials.gov/show/NCT03685162 Recruiting L.Molteni & C. dei F.lli Alitti-Soc. di Esercizio S.p.A. 2023-02-28
NCT03684317 Primary Dependence to Analgesic Drugs https://ClinicalTrials.gov/show/NCT03684317 Recruiting University Hospital, Toulouse 2021-04-30
NCT03583138 HIV, Buprenorphine, and the Criminal Justice System (STRIDE2) https://ClinicalTrials.gov/show/NCT03583138 Completed Yale University 2015-12-15
NCT03509077 Study of Addiction Criteria in the Elderly https://ClinicalTrials.gov/show/NCT03509077 Recruiting University Hospital, Toulouse 2019-06-19
NCT03483220 Effect of Impulsivity and Decision Making Style on Brain Volume https://ClinicalTrials.gov/show/NCT03483220 Enrolling by invitation Assiut University 2019-08-31
NCT03462797 Opioid Physiology Project https://ClinicalTrials.gov/show/NCT03462797 Completed University of Tennessee 2018-10-05
NCT01248767 A Prospective Clinical Study of a Cohort of Patients Seeking Treatment for a Behavioral Addiction https://ClinicalTrials.gov/show/NCT01248767 Recruiting Nantes University Hospital 2026-08-31
NCT01038245 Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smokers and in Heavy and Light Situational Smokers https://ClinicalTrials.gov/show/NCT01038245 Completed National Institutes of Health Clinical Center (CC) NA
NCT03297853 Prevalence, Management and Follow-up of Patients With Addiction to Opioid Analgesics https://ClinicalTrials.gov/show/NCT03297853 Completed University Hospital, Montpellier 2017-07-31
NCT02849574 Evaluation of Changes in Consumption of Drugs and Substances After Incarceration https://ClinicalTrials.gov/show/NCT02849574 Completed Nantes University Hospital 2015-01-31
NCT02245685 Longitudinal Followup of Patients Under Substitution Therapy From the Moment They Enter a Specialized Care Center for Addicts to the Period They Are Monitored by a General Practitioner Outside the Specialized Care Center https://ClinicalTrials.gov/show/NCT02245685 Completed Nantes University Hospital 2014-06-30
NCT00751426 Treatment of Hepatitis C in Psychiatric Patients https://ClinicalTrials.gov/show/NCT00751426 Completed Charite University, Berlin, Germany 2002-02-28
NCT00491335 HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers https://ClinicalTrials.gov/show/NCT00491335 Completed National Institutes of Health Clinical Center (CC) NA
NCT00350493 Three Year Follow up of a Randomised Controlled Trial (RCT) of an Intervention for Tobacco Dependence Among Those With a Psychotic Illness https://ClinicalTrials.gov/show/NCT00350493 Completed The University of New South Wales 2006-02-28
NCT00292136 Real Time Assessment of Drug Craving, Use, and Abstinence During Outpatient: A Development and Feasibility Study https://ClinicalTrials.gov/show/NCT00292136 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02974335 A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements (CDEs) Into the Electronic Health Record (EHR) in Large Primary Care Settings (“CDE-EHR-PC” Study), Phase 1 https://ClinicalTrials.gov/show/NCT02974335 Completed NYU Langone Health 2019-04-05
NCT04336605 Killing Pain - Use of Analgesic, Sedative and Anxiolytic Medication and the Development of Psychiatric Illness in Adolescents https://ClinicalTrials.gov/show/NCT04336605 Active, not recruiting Norwegian Center for Violence and Traumatic Stress Studies 2023-01-31